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#MindfulMondays with Miss SA

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Research on Depression in the Workplace.

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Mental Health Matters Journal for Psychiatrists & GP's

MHM Volume 8 Issue1

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If you are a journalist writing a story contact Kayla on 011 234 4837  media@anxiety.org.za


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It’s the small things that make a BIG difference. Sign up for the “My School | My Village | My Planet” Card and start making a difference to Mental Health in South Africa today.

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Literacy is a luxury that many of us take for granted. That is why SADAG created SPEAKING BOOKS and revolutionized the way healthcare information is delivered to low literacy communities.

The customizable 16-page book, read by local celebrity audio recordings, ensures that vital health and social messages can be seen, heard, read and understood by everyone across the world.

We started with books on Teen Suicide prevention , HIV, AIDS and Depression, Understanding Mental Health and have developed over 100+ titles, such as TB, Malaria, Polio, Vaccines for over 45 countries.

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Q. How do drugs taken once a week, once a month or even once a year do their work?

A. There are three basic mechanisms, said Dr. Marcus M. Reidenberg, head of the clinical pharmacology division of NewYork-Presbyterian Hospital/Weill Cornell Medical Center.

First, “some of the medications are given in a very sustained-release formulation,” he said. Some are injections of tiny crystals that take days or weeks to dissolve and be absorbed. For some, “the chemical is encased in a plastic cylinder and slowly diffuses through the plastic.” Norplant, a birth-control implant, takes five years to diffuse, he said, the longest period he knows of.

For some drugs, a single dose has a long-lasting effect where it ends up in the body. For example, “the ones for osteoporosis go to the bone and bind there and stay,” Dr. Reidenberg explained. “They go to the bone mineral crystal, where they inhibit the action of cells called osteoclasts that normally break down bone.” Other cells, osteoblasts, build bone in a continuing cycle.

“The drug changes the balance of the cycle, so that the total bone mass stops going down,” Dr. Reidenberg said.

Still other drugs prompt a series of events in the body that take much longer for completion, he said. “The drugs used in chemotherapy all produce their effects on the target cells in a matter of hours,” he said. “But the consequences develop that produce the therapeutic effect” over a long period.


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